Chapter 20 - Antifungal Therapy
Jan 15, 2021 | Chemical Pathology
Amphotericin B is a polyene antifungal drug that is both fungistatic and fungicidal depending on the concentration at the infection site and the susceptibility of the pathogen. It acts by binding to sterols, primarily ergosterol in the fungal cell membrane of susceptible fungi with a resultant change in membrane permeability which allows leakage of intracellular components....
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