Apr 05, 2023 | Chemical Pathology
This manual, updated November 2022, serves to strengthen medical surveillance through clinical management, relieving uncertainty about the implications of illness for working life, and enabling sound advice on the steps to be taken for the best outcome....
Nov 01, 2018 | Chemical Pathology
Cadmium (Cd), chromium (Cr), arsenic (As) and nickel (Ni) are some of the most widely-studied heavy metals, for their roles in oxidative stress. These metals are classified as Group 1 carcinogens to humans, according to the International Agency for Research on Cancer (IARC).2 The major cancer sites are lung, bladder, skin, nasal cavity and sinuses. Together with environmental pollution that causes excessive exposure to heavy metals, occupational exposure increases heavy metal body burden. Detoxification methods should be investigated, and implemented as part of medical surveillance programmes....
Jul 31, 2018 | Chemical Pathology
Exposure to heavy metals represents a significant health concern in the workplace. These metals have the ability to induce a number of adverse health effects but their role in carcinogenesis is of most concern. Metals as workplace carcinogens will be discussed in two parts. Part I will focus on the mechanism of carcinogenesis, and Part II will focus on oxidative stress and the role that antioxidants can play in the prevention of occupational cancer....
May 31, 2018 | Genetics
Cadmium (Cd) is a naturally occurring heavy metal that usually complexes with other elements, such as zinc, lead and chloride....
Mar 31, 2018 | Chemical Pathology
Cancer is one of the leading causes of death worldwide, with around 14 million new cases in 2012.1 Cancer accounted for 8.8 million deaths in 2015.2 Several risk factors play a role in the development of cancer....
Nov 30, 2017 | Chemical Pathology
Inorganic lead is a cumulative toxic metal found ubiquitously in the environment and was one of the first metals to be used in industry. Hence, occupational diseases associated with lead exposure were the first to be described. Workers are exposed to lead during production, use, maintenance, recycling and disposal of lead material and products. Exposure is encountered in various industrial sectors such as construction, manufacturing, wholesale trade, transportation and remediation, and even through hobbies....
May 31, 2017 | Chemical Pathology
People are living and working longer and, for the first time in history, five generations will be working side by side. Even though the lives of workers have changed, society’s idea about what constitutes an ideal worker has not....
May 31, 2017 | Chemical Pathology
Substance abuse in the workplace is becoming increasingly common. Work performance can be severely affected, resulting in huge costs to the employer. Substance abuse is a dismissible offence according to the Commission for Conciliation, Mediation and Arbitration (CCMA)....