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Lab Update 45 - The Anti-PLA2 Receptor Antibodies Test

Oct 09, 2023 | Immunology

Primary membranous nephropathy Kidney disease Anti-PLA2 Antibodies

Membranous nephropathy (MN) is characterised by a thickening of the glomerular capillary walls due to immune complexes that are formed on the outer surface of the basement membrane. MN is the most common cause of nephrotic syndrome in adults without underlying diabetes mellitus. The diagnosis of MN should be considered in all adult patients who present clinically with nephrotic syndrome (including features such as proteinuria, hypoalbuminemia, edema and weight gain)....

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