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AmpathChat #53 - Molecular Testing In Colorectal Carcinoma


Apr 01, 2019 | Histopathology

Dr Robert M. Maritz & Dr Jaysen Knezovich

Colorectal carcinomas arise from colorectal epithelium, which has undergone a series of molecular changes, referred to as the adenoma-carcinoma progression sequence. With increasing genetic mutations, progression from normal epithelium to adenomas with dysplasia occurs. Eventually, adenomas that show high-grade dysplasia give rise to invasive colorectal carcinomas.

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